Assoc Sci I, Injectable Drug Product Development
Alexion

This is what you will do:

The Associate Scientist I will join Injectable Drug Product Development group to support the development of Alexion's biotherapeutic candidates. This individual will develop injectable formulations with fit for purpose analytical methods, perform analytical testing, and draft reports for the executed studies. This individual will work independently in a dynamic team environment and routinely collaborate with other members of Injectable Drug Product Development as well as other groups in Product Development and Clinical Supply.

You will be responsible for:

• Execution of formulation screening and stability studies for injectable drug products including proteins, siRNAs, peptides.
• Supporting analytical method development and optimization
• Supporting development and tech transfer of GMP fill finish processes to internal and external manufacturing organizations.
• Writing internal technical reports on the executed studies
• Assisting in preparation of external regulatory submissions for the Alexion product candidates.
• Participate in department meetings and other technical and team building activities.

You will need to have:

• With some supervision, design and execute phase appropriate formulations and fill finish processes.
• Good understanding of protein chemistry and stability, and degradation mechanism.
• Ability to work in a collaborative setting and adhere to timelines.
• Demonstrated ability to work effectively in a cross-functional settings.
• Hands-on experience with liquid chromatography methods (e.g. SEC, IEX, HIC) and capillary methods (e.g. iCE, LabChip GXII Touch).
• Strong knowledge of analytical software (e.g. Empower, JMP).
• Experience with electronic record keeping software, like ELN.
• The duties of this role are generally conducted in an lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious, and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

We would prefer for you to have:

• BS or MS degree in Biochemistry, Chemistry, Chemical Engineering or related discipline from an accredited university with with 0-2 years of experience.
• Excellent interpersonal and communication skills.
• Understanding of the biotechnology products life cycle and factors impacting product stability.
• Knowledge of cGMP and quality guidelines.
• High level proficiency in MS Office software including Word, Excel, Outlook, and PowerPoint

Expectation of working in the office 4 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Date Posted
03-May-2024

Closing Date
27-Jun-2024Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact accommodations@Alexion.com. Alexion participates in E-Verify.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

This job has expired.