Senior Scientist, Translational Bacteriology
AstraZeneca

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies.

At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

We are seeking a highly motivated Senior Scientist who has an extensive scientific expertise in microbiology with an emphasis on developing novel vaccine candidates and antimicrobial products for bacterial pathogens . The successful candidate will have specialized experience in designing and conducting laboratory experiments to study vaccine and mAb pharmacodynamics, and will develop and qualify methods, as well as generate, interpret and report scientific data. Candidate should be proficient in troubleshooting and hold PhD in Microbiology, Immunology, Vaccinology or related field, with proven post-doctoral record experience.

As a Senior Scientist in our Early Vaccines and Immune Therapies group you will be a key member of a team focused on supporting projects in clinical development. You will bring your theoretical and practical expertise in microbiology to establish assay systems and deliver datasets that will have direct impact on patients.

What Does This Role Involve?

• Execute biochemical and cell-based assays to characterize candidate vaccines and mAbs targeting bacterial pathogens
  
• Apply molecular biology skills to generate recombinant proteins and bugs
  
• Develop and qualify bioanalytical assays to characterize candidate drugs
  
• Assist in the preparation and review of bioanalytical data and reports suitable for regulatory submission
  
• Communicate across the team and with senior management
  

Essential Skills and Capabilities

• PhD in microbiology, immunology, vaccinology, or equivalent with some postdoctoral training
  
• Background in molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing , RT-PCR, and qPCR.
  
• Extensive experience in studying bacterial pathogens and pathogenesis
  
• Experience in bacterial and mammalian cell culture, cytotoxicity and opsonophagocytic killing assays.
  
• Ability to evaluate data quality, troubleshoot, and interpret experimental results
  
• Meticulous tracking and documenting of results in laboratory notebooks, databases, and scientific reports
  
• Strong verbal and written communication skills
  

Desirable for the role

• Ability to multitask and prioritize numerous different projects
  

• Job complexity: Must be able to understand, conduct and interpret results of technically challenging experiments with supervision
  
• Strong interpersonal and collaborative skills together with evidence of having used these to support problem solving and delivery in a team-oriented, collaborative environment
  
• Ability to work in a collaborative, fast-paced environment while planning and meeting timelines
  
• Proven track record of success in your research and experience preparing written scientific reports (e.g. manuscripts) and oral presentations (e.g. slides, posters)
  

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what's next?

Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it's yours.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

This job has expired.