Research Technician, Herman B Wells Center of Pediatric Research
Indiana University

Department

PED-ENDOCRINOLOGY BASIC RES (IN-PENB-IUINA)

Department Information

The Herman B Wells Center for Pediatric Research conducts basic science and translational research within the Department of Pediatrics at Indiana University School of Medicine (IUSM). The Wells Center houses more than 200 faculty investigators, staff, and trainees seeking answers to the most pressing questions related to childhood illness.

With the collaboration between scientists and physicians, the center aims to increase knowledge of causes and mechanisms of serious pediatric diseases. Our goal is to develop innovative approaches to the diagnosis and treatment of sick children in Indiana and beyond.

The Center for Diabetes and Metabolic Diseases is a highly interactive and diverse research environment with a strong history of mentoring and career development of junior scientists. In addition to a rich research environment, the Center and School of Medicine provide numerous scientific seminar series, career development workshops, and the opportunity to interact with a diverse pool of international scientists.

As the nation's largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and well-being for all throughout the state of Indiana.

Job Summary

Research projects in this laboratory will focus on characterizing the function role of co-regulators recruited to islet-enriched transcription factors in the beta cell with an emphasis on understanding how their interactions are influenced by diabetes pathogenesis. This research makes extensive use of molecular biology including cell culture propagation, RNAi gene modulation, Western blotting, real-time PCR, CRISPR, immunofluorescence, lentivirus preparation, and significant amount of animal research.

Department-Specific Responsibilities

• Assists the Principal Investigator (PI), senior Research Technician, and graduate students in conducting research focusing on islet beta cell function and diabetes development within the Wells Center for Pediatric Research.
• Responsible for mouse colony management, including tail tip and genotyping.
• Responsible for intraperitoneal glucose tolerance tests, and collection of serum from unrestrained mice.
• Performs postmortem acquisition of mouse tissues, including fixation, embedding and sectioning.
• Responsible for daily monitoring and data acquisition: This will entail monitoring rodents that have undergone procedures and tracking experimental outcomes. Some outcomes include: blood draw & complete blood counts, necropsy & harvest of tissues, and measurement/documentation of tumor progression.
• Conducts tissue culture experiments including knockdown/knockout experiments (siRNA/shRNA/CRISPR), qPCR, ELISA, Western blotting and flow cytometry.
• Prepares official data reports and distribution to investigators.
• Ensures institutional compliance records are accurate to maintain core compliance, such as IACUC, Biosafety, Laboratory Safety, and Radiation Safety.
• Responsible for preparation of research reports, maintenance of laboratory equipment records, and maintaining inventory of laboratory supplies.
• Operates and maintains specialized software and laboratory equipment, including software updates and equipment repairs; maintains supply inventory and ordering process.

General Responsibilities

• Performs a wide variety of complex experiments and reports results.
• Keeps organized analytical data of performed experiments.
• Provides support for equipment maintenance as needed.
• Acts as a liaison to students and laboratory personnel for training.
• Maintains laboratory supply requisition and management.
• May train junior-level staff.
• May help plan experiments or short-term goals.

Qualifications

EDUCATION

Required

• Bachelor's degree in science or related field

Combinations of related education and experience may be considered

SKILLS

Required

• Proficient communication skills
• Maintains a high degree of professionalism
• Demonstrated time management and priority setting skills
• Demonstrates a high commitment to quality
• Possesses flexibility to work in a fast paced, dynamic environment
• Highly thorough and dependable

Preferred

• Excellent organizational skills to maintain colony

Working Conditions / Demands

The role regularly requires the ability to effectively communicate. The role frequently requires the ability to move about the work environment and to position oneself to operate laboratory equipment effectively. The role requires the ability to move objects weighing up to 25 pounds and will occasionally work near moving mechanical parts. The person in this role must be able to perform the essential functions with or without an accommodation.

Work Location

Indianapolis, Indiana

Advertised Salary

The salary range for this position is $37,000 - $42,000. Salary determination is based on experience, skill level, education, and training.

Benefits Overview

For full-time staff employees, Indiana University offers a wide array of benefits including:

• Multiple plan options for medical insurance
• Dental insurance
• Health Savings Account with generous IU contribution
• Life insurance, LTD, and AD&D options
• Base retirement plan contribution from IU, subject to vesting
• Additional supplemental retirement plan options
• Tuition benefit for IU classes
• 10 paid holidays per year
• Generous Paid Time Off
• Paid Parental Leave
• Employee Assistance Program (EAP)

Learn more about our benefits by reviewing our online Benefits Brochure.

Job Classification

Career Level: Intermediate

FLSA: Nonexempt

Job Function: Research

Job Family: Research Analysis

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Posting Disclaimer

Due to the COVID-19 pandemic, there may be differences in the working conditions as advertised in our standard job postings (e.g., the ability to travel from one campus to another, etc.). If you are invited for an interview, please discuss your questions or concerns regarding the working conditions at that time.

This posting is scheduled to close at 11:59 pm EST on the advertised Close Date. This posting may be closed at any time at the discretion of the University, but will remain open for a minimum of 5 business days. To guarantee full consideration, please submit your application within 5 business days of the Posted Date.

If you wish to include a cover letter, you may include it with your resume when uploading attachments.

New employees will be provided with information regarding Indiana University's COVID-19 vaccine policy, which includes the opportunity to request an exemption. To learn more, view our COVID-19 vaccine information page.

Equal Employment Opportunity

Indiana University is an equal employment and affirmative action employer and a provider of ADA services. All qualified applicants will receive consideration for employment based on individual qualifications. Indiana University prohibits discrimination based on age, ethnicity, color, race, religion, sex, sexual orientation, gender identity or expression, genetic information, marital status, national origin, disability status or protected veteran status. Indiana University does not discriminate on the basis of sex in its educational programs and activities, including employment and admission, as required by Title IX. Questions or complaints regarding Title IX may be referred to the U.S. Department of Education Office for Civil Rights or the university Title IX Coordinator. See Indiana University's Notice of Non-Discrimination here which includes contact information.

Campus Safety and Security

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Telephone: 812-856-1234

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